Saracens are still licking their wounds after a disappointing 20-28 home defeat against Leicester last week, a result which cost them their leading position in the table.
Their last meeting against the Chiefs was at Allianz Park in November and ended in a close 18-20 loss.
Callum Clark will be missing from the action on Saturday after suffering a broken arm in their game against Tigers last weekend, adding another name to the growing list of injured players this season.
The Chiefs regained their table top position last week after a hard-fought win against Northampton, ending a three-match losing streak.
Saracens, now second in the table, trail the Chiefs by only four points but with Wasps close on their heels in third, the Men in Black will need a strong performance in Saturday’s game.
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