This round’s fixtures will provide a repeat of the opening weekend of the season, with some crucial matches taking place at both ends of the table.
Friday night sees Sale entertain Harlequins at the AJ Bell Stadium in a potentially pivotal match in the quest for a playoff place.
With five matches remaining, Sale sit in sixth place and trail fourth-place Harlequins by nine points. The home side had the opportunity to make up ground last time out with a trip to bottom side Newcastle Falcons but a 22-17 defeat was a missed opportunity to close the gap and they can’t afford to slip up this weekend.
Harlequins will be buoyed by their first-half performance against Saracens a fortnight ago as they established a 17-6 lead with tries from Marcus Smith and Danny Care. But they were unable to see it out and Saracens hit back in the second half with three tries to win 27-20.
Bath take on Bristol at Twickenham and whilst they sit in seventh place and ten points off the top four, a victory on Saturday coupled with Sale beating Harlequins could bring them right back into the playoff picture.
Bristol meanwhile will be more than happy to just confirm their place in the Gallagher Premiership for next season and a couple of wins from their last five matches could well confirm that.
Reigning champions Saracens entertain Newcastle Falcons after their thrilling comeback win at London Stadium, and with a 12-point advantage over third-placed Gloucester they will be confident of securing a home semi-final over the next couple of weeks.
There’s another couple of fascinating tussles at the bottom taking place on Saturday as more sides look to move away from the foot of the table.
Worcester make the trip to Wasps looking to build on their fine win at Bristol last time out, and with Newcastle facing a tough fixture this presents a fantastic chance to increase the gap.
Leicester, who are only two points better off than Worcester, take on leaders Exeter knowing that if results don’t go their way then they could be facing a tricky last four matches.
The weekend’s other fixture sees Northampton entertain fellow playoff chasers Gloucester.
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