The 20-18 loss was Saracens’ first home league defeat since March 2016, and meant that Exeter extended their lead at the top of the table to five points.
Attention now turns to Harlequins on Sunday, with Saracens looking to keep the pressure up at the top before back-to-back Champions Cup fixtures in December.
Saracens will be hoping to have as many of their international contingent back as possible ahead of this weekend, with the likes of Owen Farrell and Maro Itoje on England duty for the Autumn Internationals.
Whilst Mark McCall has been able to name a strong side in recent weeks, the absence of several first-team players has meant that his resources have been slightly stretched.
Saracens will also have one eye on revenge this weekend following a defeat against Harlequins in the Anglo-Welsh Cup a month ago, despite the fact that this weekend’s teams are likely to be much different.
Harlequins come into the game on the back of consecutive defeats against Exeter and Bath, which has turned their encouraging start to the season into a campaign that could turn into mid-table obscurity unless they pick up some points over the Christmas period.
But again, the hosts will have a sprinkling of international stars available again and that should prove a timely boost ahead of an important run of fixtures.
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