The action begins on Saturday as the Men in Black take on Northampton Saints at Twickenham Stadium as part of the London Double Header.
From there they will be packing their bags as they prepare for two weeks on the road, first heading to The Rec to take on Bath on Saturday 9th September.
Saracens will then be heading stateside to face the Newcastle Falcons in Philadelphia, only the second Premiership Rugby game to take place in USA.
One man who will be absent is Billy Vunipola, who is still recovering from the knee injury that forced him to bow out of the British and Irish Lions tour of New Zealand. Mark McCall hopes this will only be a short-term absence and is keen to have the England number eight back as soon as possible.
With six other Lions players in the Saracens squad, some are likely to be rested early in the season following their demanding tour of New Zealand. This leaves an opening for new arrivals to shine, including the returning Will Skelton, and new faces Dominic Day, Christopher Tolofua, Calum Clark, Kieran Longbottom, and Liam Williams.
Saracens will also be in high spirits following a successful preseason, including their seven-try victory against Timisoara Saracens. With a tricky opening to the campaign, the back-to-back European champions will be hoping this confidence will continue and lead them to a strong start of the season.
They have been handed a timely boost this week with the news that England fly-half Owen Farrell has signed a new five-year deal, keeping him at the club until 2022.
SARACENS VS NORTHAMPTON SAINTS
SATURDAY 2ND SEPTEMBER, TWICKENHAM STADIUM
15 ALEX GOODE
14 SEAN MAITLAND
13 DUNCAN TAYLOR
12 BRAD BARRITT
11 NATHAN EARLE
10 ALEX LOZOWSKI
9 RICHARD WIGGLESWORTH
1 RICHARD BARRINGTON
2 SCHALK BRITS
3 VINCENT KOCH
4 DOMINIC DAY
5 GEORGE KRUIS
6 MARO ITOJE
7 SCHALK BURGER
8 JACKSON WRAY
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