The Men in Black will be hoping for a strong start after reaching the semi-finals last season. They are in Pool Three of the competition alongside Northampton, Worcester and Scarlets.
Saracens have had a fantastic season so far, having lost only one game, and are currently top of the Premiership table after an impressive 44-13 victory over London Irish last weekend.
Mark McCall’s men are two points clear of reigning champions Exeter Chiefs, whilst there is now a seven-point gap to Leicester Tigers who sit in third place.
The defence of their Champions Cup crown has also started well following consecutive victories over Northampton Saints and Ospreys, as Saracens look to mount a silverware challenge on multiple fronts.
Harlequins on the other hand have had a mixed start to their season, and come in to Sunday’s game after narrowly avoiding defeat to the Premiership’s bottom club, Worcester.
Quins are likely to be without winger Marland Yarde, after he wasn’t selected for their last two games following news of a controversial impending mid-season transfer to Sale.
BT Sport will be showing the game live as they continue their commitment to the competition this season by screening two matches of the cup in each round.
In other news, six Saracens players have been named in Eddie Jones’ squad ahead of England’s clash with Argentina for the Autumn Internationals. The players who have made it into the squad are; Owen Farrell, Nick Isiekwe, Maro Itoje, George Kruis, Jamie George and Mako Vunipola.
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