The action kicks off at 19:45pm on Friday as the Men in Black search for their fourth win of the season, following their convincing 41-13 win against Sale Sharks at Allianz Park last week.
Saracens, one of the pre-season favourites for the Premiership title, will hope to emulate the strong offensive play seen in their last two games.
After four games, Saracens have already racked up a mammoth 146 points, 16 more than league leaders and reigning champions Exeter Chiefs.
Despite showcasing an impressive attacking style of rugby so far, last week’s man of the match Owen Farrell believes that there is much more for the team to do in their pursuit of perfection.
“When you are in the high scoring games and you seem to be attacking well - there is no excuse - but people normally do start focusing on that attacking side…We need to try and make sure that we get our full game onto the pitch next week,” said Farrell.
One man who will be absent for the trip to Worcester will be Billy Vunipola. The England number eight will be sidelined for four months after suffering a knee-cartilage injury in the win over Sale.
Mark McCall, Saracens Director of Rugby, said: “For any team to lose a player of the ability of Billy is a blow and he will be missed through the autumn for both Saracens and England.”
“What’s now important for Billy is his recovery and we look forward to his return later this season.”
Worcester are still searching for their first win of the season, with last weekend’s defeat to rivals Gloucester their fourth successive defeat.
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